Nicole C. Riddle

The paper identifies common and sex-biased aging biomarkers in skeletal muscle transcriptomes across six species, revealing shared and divergent molecular mechanisms of aging.

This study compares transcriptomic profiles of embryonic stem cells across mammals, identifying conserved and species-specific pluripotency mechanisms and markers.

This study identifies sex-biased gene expression, alternative splicing, and isoform dynamics in bovine embryos, linking male-biased metabolism to faster development and female-biased X-linked gene expression to sex-specific regulation.

The paper examines sex differences in DNA methylation across 14 bat species, finding female hypermethylation on the X chromosome and associations between methylation patterns and sexual selection.

This study examines how exercise affects climbing ability in Drosophila melanogaster, finding significant variation and sex- and genotype-dependent responses.

The paper examines the genome-wide binding of HP1 proteins in Drosophila and finds they are associated with active transcription and RNA polymerase pausing, challenging the notion that chromatin context alone determines their function.

The paper uses GWAS in Drosophila to identify molecular pathways controlling weight and exercise-induced weight changes, finding CNS involvement and signaling pathway importance.

The paper identifies genetic factors influencing basal and induced activity levels in Drosophila melanogaster using a genetic reference panel and exercise assays.

The paper identifies HP1B as a Drosophila euchromatic HP1 protein, showing its role in metabolism through altered food intake, body fat, and gene expression.