Jingyue Ellie Duan

The paper identifies common and sex-biased aging biomarkers in skeletal muscle transcriptomes across six species, revealing shared and divergent molecular mechanisms of aging.

This study uses single-nucleus RNA-seq to analyze cell type-specific responses to heat stress in bovine mammary glands, identifying changes in gene expression, proteostasis, and intercellular communication.

This study creates a cross-species single-cell transcriptomic atlas of early ovarian development in cattle, human, and mouse, identifying shared and species-specific cell types and genes.

This paper generates bovine formative embryonic stem cells with dual developmental plasticity, capable of differentiating into various embryonic and extraembryonic cell types.

This study identifies sex-biased gene expression, alternative splicing, and isoform dynamics in bovine embryos, linking male-biased metabolism to faster development and female-biased X-linked gene expression to sex-specific regulation.

This study identifies transcriptomic changes in bovine mammary epithelial cells under heat stress and during recovery, revealing gene expression patterns related to differentiation, heat shock response, and recovery mechanisms.

The paper identifies CLAMP as a transcription factor that regulates heat stress-induced repression of constitutive genes in Drosophila and presents a high-resolution 3D genomic dataset.

The paper shows that CLAMP and Zelda work together to drive zygotic genome activation in Drosophila by enhancing chromatin accessibility and promoting transcription.