Richard P. Meisel

Common and Sex-Biased Muscle Transcriptomic Aging Signatures Across Diverse Species

The paper identifies common and sex-biased aging biomarkers in skeletal muscle transcriptomes across six species, revealing shared and divergent molecular mechanisms of aging.

X-Y divergence of house fly (Musca domestica) proto-sex chromosomes follows distinct evolutionary trajectories despite residing in the same genome

The paper examines sex chromosome evolution in house flies, finding both canonical and non-canonical divergence patterns despite shared genomic context.

House fly proto-Y chromosomes differentially affect courtship success regardless of social context and female type

The study investigates how genetic variation in male reproductive traits is maintained in house flies by testing genotype-by-environment interactions, female preference, and male age effects.

Drosophila pseudoobscura third chromosome inversion arrangements have temperature-dependent and sex-specific effects on life history traits

This study examines the effects of chromosomal inversion arrangements in Drosophila pseudoobscura on life history traits, finding support for the coadaptation hypothesis over pleiotropy.

A population genomic resource for Drosophila pseudoobscura

The paper presents a population genomic resource for Drosophila pseudoobscura, analyzing 60 sequenced genomes to study chromosomal structure and genetic variation across the species' geographic range.

Genotype and environmental effects shape the house fly microbiome (Musca domestica)

This study examines how temperature and host genotype influence the microbiome of house flies, finding temperature has a stronger effect than genotype, but no dysbiosis was observed.

Comparative Transcriptomic Analysis of Embryonic Stem Cells (ESCs) across Mammalian Species

This study compares transcriptomic profiles of embryonic stem cells across mammals, identifying conserved and species-specific pluripotency mechanisms and markers.

Sex-biased Transcriptome in in vitro Produced Bovine Early Embryos

This study identifies sex-biased gene expression, alternative splicing, and isoform dynamics in bovine embryos, linking male-biased metabolism to faster development and female-biased X-linked gene expression to sex-specific regulation.

Frequencies of house fly proto-Y chromosomes across populations are predicted by temperature heterogeneity within populations

The paper measures proto-Y chromosome frequencies in house fly populations across the U.S. and finds that temperature range, not latitudinal clines, explains their distribution.

Testis- and ovary-expressed polo transcripts and gene duplications affect male fertility when expressed in the germline

The paper investigates the evolutionary and functional differences between duplicated Plk genes in Drosophila, showing that Dpse-polo-dup1 improves male meiotic spindle regulation and reduces male infertility.

Induction and inhibition of Drosophila X chromosome gene expression are both impeded by the dosage compensation complex

The paper examines how DCC binding affects gene expression changes on the X chromosome in Drosophila under various treatments, finding that DCC-bound genes are less likely to be up- or down-regulated.

The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

The paper investigates the homology between the X chromosomes of the German cockroach and flies, finding conserved genes and dosage compensation despite 400 million years of divergence.

Minimal effects of proto-Y chromosomes on house fly gene expression in spite of evidence that selection maintains stable polygenic sex determination

The paper examines the effect of proto-Y chromosomes on gene expression in house flies and finds minimal effects despite evidence of selection maintaining polygenic sex determination.

Functional genomics of the stable fly, Stomoxys calcitrans, reveals mechanisms underlying reproduction, host interactions, and novel targets for pest control

This study provides insights into the biology of the stable fly by combining genome sequencing, microbiome analysis, and RNA-seq to identify genes related to reproduction, host interactions, and pest control.

The Glossina Genome Cluster: Comparative Genomic Analysis of the Vectors of African Trypanosomes

The paper presents a comparative genomic analysis of six Glossina species, identifying genetic features related to their unique biology and vectorial capacity.

Genes relocated between Drosophila chromosome arms evolve under relaxed selective constraints relative to non-relocated genes

The paper investigates the evolutionary constraints on relocated genes in Drosophila, finding they evolve faster and are less essential than non-relocated genes but more constrained than canonical duplicates.