CD27+ γδ T Cells Drive Plaque Instability in Advanced Atherosclerosis: Targeting CXCR3 for Therapeutic Intervention
Peter Kanellakis, Anh Cao, Yi Ee Lye, Ban‐Hock Toh, Alex Bobik, Tin Soe Kyaw
This study identifies CD27+ γδ T cells as key drivers of atherosclerotic plaque instability and shows that targeting CXCR3 with AMG487 improves plaque stability.
bioRxiv · Aug 19, 2025 · PreprintImmunology