Author

Peter Kanellakis

Baker Heart and Diabetes Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alex BobikiD· 3 shared K ouml nig PeteriD· 2 shared Tin Soe KyawiD· 2 shared Yi Ee Lye· 2 shared Aidan P. G. WalshiD· 1 shared Alexander Ruvantha PintoiD· 1 shared Ana C. Maluenda· 1 shared Anastasia Barbaro-WahliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Alex BobikORCID

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3 papers

Recent·Most cited

Immune-Mediated Necrotic Cell Death Initiated by Stressed Cardiomyocytes is a Major Contributor to Cardiomyocyte Loss Following Myocardial Infarction

Tin Soe Kyaw, Peter Kanellakis, Anne Le, Yi Ee Lye, Pranjal Patel, Kurt Brassington, Nalin Dayawanmsa, Hericka Bruna Figueiredo Galvão, Grant Raymond Drummond, Christopher Graeme Sobey, Alex Bobik, K ouml nig Peter

This study shows that cytotoxic γδ-T cells contribute to cardiomyocyte death after myocardial infarction, and targeting STING and type I interferon pathways reduces infarct size.

bioRxiv · May 5, 2026 · PreprintImmunology

Autoimmune-like CD8⁺ T Cell Responses Drive Atherosclerotic Plaque Instability and Predict Cardiovascular Events

Jonathan Edward Noonan, Nicholas Borcherding, Sander W. van der Laan, Nicholas A. Gherardin, Moustafa I Morsy, Joshua I. Gray, Lisa Maria Domke, Anna M.D. Watson, Angela Huang, Anastasia Barbaro-Wahl, Shania A Prijaya, Marcel Michla, Zahra Elahi, Yilu Huang, Nalin H. Dayawansa, , K ouml nig Peter

This study identifies autoimmune-like CD8⁺ T cell responses as drivers of atherosclerotic plaque instability and predictors of cardiovascular events in humans and mice.

bioRxiv · Apr 29, 2026 · PreprintImmunology

CD27+ γδ T Cells Drive Plaque Instability in Advanced Atherosclerosis: Targeting CXCR3 for Therapeutic Intervention

Peter Kanellakis, Anh Cao, Yi Ee Lye, Ban‐Hock Toh, Alex Bobik, Tin Soe Kyaw

This study identifies CD27+ γδ T cells as key drivers of atherosclerotic plaque instability and shows that targeting CXCR3 with AMG487 improves plaque stability.

bioRxiv · Aug 19, 2025 · PreprintImmunology