SOX2 drives fetal reprogramming and reversible dormancy in colorectal cancer
Anna Baulies, Verónica Moncho-Amor, Diana Drago Garcia, Ania Kucharska, Probir Chakravarty, Manuel Moreno‐Valladares, Sara Cruces‐Salguero, Florian Hubl, Colin Hutton, Hanue Kim, Ander Matheu, Robin Howard Lovell-Badge, Vivian Sze Wing Li
This paper shows SOX2 induces fetal reprogramming and reversible dormancy in colorectal cancer, promoting tumour progression and drug tolerance.
bioRxiv · Sep 11, 2024 · PreprintCancer Biology