Aerobic glycolysis and lactate regulate histone H3K18Lactylation occupancy to fine-tune gene expression in developing and mature retina
Mohita Gaur, Xulong Liang, Matthew J. Brooks, Ke Jiang, Anjani Kumari, Milton A. English, Paolo Cifani, Maria C. Panepinto, Jacob K. Nellissery, Robert N. Fariss, Laura Campello, Claire Marchal, Anand Swaroop
The paper shows that glycolysis and lactate regulate histone H3K18 lactylation to control gene expression in retinal development and maturation.
bioRxiv · Apr 17, 2025 · PreprintMolecular Biology