Innocent until proven guilty: Tannerella forsythia may attenuate the virulence of Porphyromonas gingivalis
Mirosław Książęk, Małgorzata Benedyk‐Machaczka, Alicja Sochaj-Grzegorczyk, Danuta Mizgalska, Irena Waligórska, Magdalena Nowak, Anna Kaczor, Barbara Potempa, Andrew Fuchs, Ida B. Thøgersen, Jan J. Enghild, Carsten Scavenius, Piotr Mateusz Mydel, Juhi Bagaitkar, Jan Potempa
This study shows that Tannerella forsythia's miropin inhibits Porphyromonas gingivalis proteases, reducing its virulence and challenging Tf's role as a pathogen.
bioRxiv · Sep 5, 2025 · PreprintMicrobiology