The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress
Qiuhan Huang, Anna S. Monzel, Shannon Rausser, Rachel Haahr, Claire E. Indik, Micah J Savin, Natalia Bobba-Alves, Cynthia C. Liu, Jack Devine, Elizabeth Thompson, Catherine Kelly, Mangesh Kurade, Jeremy Michelson, Shufang Li, Kris Engelstad, , Caroline Trumpff
This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.
bioRxiv · Apr 19, 2024 · PreprintPhysiology