Author

Anna Y. Lee

Ontario Institute for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:simulation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam A. Margolin· 1 shared Adam D. EwingiD· 1 shared Andrew M. Smith· 1 shared Corey NislowiD· 1 shared Cristian Caloian· 1 shared David H. HaussleriD· 1 shared Guri N. GiaeveriD· 1 shared Gustavo A. StolovitzkyiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Adam A. Margolin

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2 papers

Recent·Most cited

Combining chemogenomic and gene-dose assays to investigate drug synergy

Hamid Kian Gaikani, Andrew M. Smith, Anna Y. Lee, Guri N. Giaever, Corey Nislow

This study combines chemogenomic and gene-dose assays to analyze drug synergy, identifying combination-specific sensitive strains that suggest mechanisms for observed synergies.

Frontiers in Fungal Biology · Jul 2, 2021Peer-reviewedGenomics

Combining accurate tumour genome simulation with crowd-sourcing to benchmark somatic structural variant detection

Anna Y. Lee, Adam D. Ewing, Kyle Ellrott, Yin Hu, Kathleen E. Houlahan, J Christopher Bare, Shadrielle M. G. Espiritu, Vincent Huang, Kristen Dang, Zechen Chong, Cristian Caloian, Takafumi N. Yamaguchi, ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, Michael Kellen, Ken Chen, , Paul Christopher Boutros

The paper benchmarks somatic structural variant detection methods using synthetic tumors and crowd-sourced submissions, finding that ensembles do not always outperform individual methods.

Genome biology · Nov 6, 2018Peer-reviewedBioinformatics