Maternal exposure to cigarette smoking induces immediate and durable changes in placental DNA methylation affecting enhancer and imprinting control regions
Sophie Rousseaux, Emie Seyve, Florent Chuffart, Ekaterina Bourova-Flin, Mériem Benmerad, Marie-Aline A Charles, Anne Forhan, Barbara Heude, Valérie Siroux, Rémy Slama, Jörg Tost, Daniel Vaiman, Saadi Khochbin, Johanna Lepeule, the EDEN mother-child cohort study group
This study identifies 344 differentially methylated regions in placental DNA linked to maternal smoking, including reversible and persistent changes in former smokers.
bioRxiv · Nov 22, 2019 · PreprintGenomics