Microglia are not required for normal postnatal brain development and cognitive function in the rat.
Emma K. Green, Xinyi Li, Yang Guo, Dylan Carter‐Cusack, Rocío Rojo, Maia Lyall, Annie Bell, Helen Zheng, Oliver Teenan, Sally M. Till, David Arthur Hume, Peter Kind, Pridans Clare
This study shows that microglia are not essential for normal postnatal brain development and cognitive function in rats, as Fireko rats lack microglia but show no behavioral differences.
bioRxiv · Dec 24, 2025 · PreprintImmunology