Author

Yang Guo

Henan Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Annie Bell· 1 shared David Arthur HumeiD· 1 shared Dylan Carter‐CusackiD· 1 shared Emma K. Green· 1 shared Helen Zheng· 1 shared Hui WangiD· 1 shared Jiangtao LuiD· 1 shared Le-Le Qiu· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

Annie Bell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IGF2BP2 links m6A-modified HMGA1 mRNA stability to mitochondrial metabolism and cell proliferation

Zhao‐Ming Cui, Jiangtao Lu, Yuan-Ye Xu, Ying-Ying Feng, Yang Guo, Yan-Ping Gao, Wen Wang, Le-Le Qiu, Xiao‐Yin Wang, Zichun Hua, Tianyun Wang, Yan‐Long Jia

This study shows IGF2BP2 enhances recombinant protein yield in CHO cells by stabilizing HMGA1 mRNA and improving mitochondrial metabolism and cell proliferation.

bioRxiv · Apr 24, 2026 · PreprintBioengineering

AlphaFold 3-powered discovery of phage proteins that inhibit bacterial transcription

Linggang Yuan, Qingyang Liu, Xiaojian Xiao, Liqiao Xu, Liang Liang, Yang Guo, Yue Yao, Hui Wang, Youjun Feng, Xiaoting Hua, Yu Feng

This study uses AlphaFold 3 to identify and characterize phage proteins that inhibit bacterial transcription, revealing novel mechanisms of action.

Cell Reports · Mar 1, 2026Peer-reviewedMolecular Biology

Microglia are not required for normal postnatal brain development and cognitive function in the rat.

Emma K. Green, Xinyi Li, Yang Guo, Dylan Carter‐Cusack, Rocío Rojo, Maia Lyall, Annie Bell, Helen Zheng, Oliver Teenan, Sally M. Till, David Arthur Hume, Peter Kind, Pridans Clare

This study shows that microglia are not essential for normal postnatal brain development and cognitive function in rats, as Fireko rats lack microglia but show no behavioral differences.

bioRxiv · Dec 24, 2025 · PreprintImmunology