Author

Ansgar Santel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Charlotte Maeve DunneiD· 2 shared Daniel TonderaiD· 2 shared Katrin RadloffiD· 2 shared Leonidas Gkionis· 2 shared Oliver KeiliD· 2 shared Akanksha MogaiD· 1 shared Angela Fischer· 1 shared Birgitt Gutbier· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPharmacology & Toxicology

Charlotte Maeve DunneORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Translational Pharmacokinetics and Pharmacodynamics of a Cationic mRNA-Lipid Nanoparticle from Mice to Non-Human Primates

Charlotte Maeve Dunne, Katrin Radloff, Leonidas Gkionis, Nourhan Kahwaji, Natscha Hartl, Oliver Keil, Angela Fischer, Gerrit Maass, Ansgar Santel, Daniel Tondera, Jorg Kaufmann

This study evaluates the pharmacokinetics and immunostimulatory effects of a cationic mRNA-LNP in non-human primates, identifying a biomarker for Tie2 signaling.

bioRxiv · Sep 29, 2026 · PreprintPharmacology & Toxicology

Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage

Katrin Radloff, Birgitt Gutbier, Charlotte Maeve Dunne, Hanieh Moradian, Marko Schwestka, Manfred Gossen, Katharina Ahrens, Laura Kneller, Yadong Wang, Akanksha Moga, Leonidas Gkionis, Oliver Keil, Volker Fehring, Daniel Tondera, Klaus Giese, , Martin Witzenrath

This study evaluates a synthetic mRNA encoding a hyperactive Ang1 fusion protein to prevent pulmonary vascular leakage in lung injury models.

bioRxiv · Oct 12, 2022 · PreprintMolecular Biology