Author

Manfred Gossen

Berlin-Brandenburger Centrum für Regenerative TherapienORCID 0000-0002-1761-4063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Charlotte Maeve DunneiD· 2 shared Akanksha MogaiD· 1 shared Andriko PalmowskiiD· 1 shared Anna Luisa HilleriD· 1 shared Ansgar Santel· 1 shared Antonia M Klaas· 1 shared Arnd KleyeriD· 1 shared Birgitt Gutbier· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

Charlotte Maeve DunneORCID

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2 papers

Recent·Most cited

BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedJan 5, 2026

Revisiting the need for mRNA nucleoside modification in CAR T cell engineering

Nourhan Kahwaji, Niklas Kotzian, Jasmin Melissa Prinz…·Norman Michael Drzeniek

This study shows that unmodified mRNA can be used for CAR-T cell engineering without compromising function, eliminating the need for costly nucleoside modifications.

7 citationstop 1%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintOct 12, 2022

Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage

Katrin Radloff, Birgitt Gutbier, Charlotte Maeve Dunne…·Martin Witzenrath

This study evaluates a synthetic mRNA encoding a hyperactive Ang1 fusion protein to prevent pulmonary vascular leakage in lung injury models.

DOI 10.1101/2022.10.12.511878

mouseexperimental assay

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