Author

Katrin Radloff

Pantherna Therapeutics GmbH, 16761 Hennigsdorf, Germany;ORCID 0009-0006-1414-7857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ansgar Santel· 3 shared Charlotte Maeve DunneiD· 3 shared Daniel TonderaiD· 3 shared Leonidas Gkionis· 2 shared Oliver KeiliD· 2 shared Akanksha MogaiD· 1 shared Angela Fischer· 1 shared Birgitt Gutbier· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

Ansgar Santel

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 12, 2026

mRNA/LNP-mediated expression of a ligand-independent Tie2 pathway activator, COMP-Tie2*, enables sustained endothelial stabilization

Katrin Radloff, Charlotte Maeve Dunne, Oliver Keil…·Daniel Tondera

This paper develops a method to sustain Tie2 activation using engineered mRNA, showing improved endothelial stabilization compared to traditional ligands.

DOI 10.64898/2026.11.10.765541

humanmultiome

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Pharmacology & ToxicologybioRxivPreprintSep 29, 2026

Translational Pharmacokinetics and Pharmacodynamics of a Cationic mRNA-Lipid Nanoparticle from Mice to Non-Human Primates

Charlotte Maeve Dunne, Katrin Radloff, Leonidas Gkionis…·Jorg Kaufmann

This study evaluates the pharmacokinetics and immunostimulatory effects of a cationic mRNA-LNP in non-human primates, identifying a biomarker for Tie2 signaling.

DOI 10.64898/2026.09.23.749423

non-human primatebulk RNA-seq

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Molecular BiologybioRxivPreprintOct 12, 2022

Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage

Katrin Radloff, Birgitt Gutbier, Charlotte Maeve Dunne…·Martin Witzenrath

This study evaluates a synthetic mRNA encoding a hyperactive Ang1 fusion protein to prevent pulmonary vascular leakage in lung injury models.

DOI 10.1101/2022.10.12.511878

mouseexperimental assay

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