Author

Anthony N. Lange

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

Corey G. K. FlynniD· 3 shared Ramy K. A. SayediD· 3 shared Troy Alan HornbergeriD· 3 shared Hector G. PaeziD· 2 shared Jamie E. HibbertiD· 2 shared Marius MeinholdiD· 2 shared Carlos S. ZepedaiD· 1 shared Christopher W. SundbergiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersPhysiology

Corey G. K. FlynnORCID

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Author profile →

3 papers

Recent·Most cited

Mechanical Loading Induces the Radial Growth of Myofibrils and Myofibrillogenesis via an mTORC1-Dependent Mechanism

Corey G. K. Flynn, Ramy K. A. Sayed, Anthony N. Lange, Wenyuan G. Zhu, Troy Alan Hornberger

This study shows that mTORC1 regulates myofibrillogenesis and radial myofibril growth in response to mechanical loading in mice.

bioRxiv · May 20, 2026 · PreprintCell Biology

Macroscopic to Ultrastructural Analyses Identify the Loss of Myofibrils as the Primary Mediator of Muscle Fiber Atrophy in Aging and Disuse

Ramy K. A. Sayed, Anthony N. Lange, Hector G. Paez, Jamie E. Hibbert, Marius Meinhold, Corey G. K. Flynn, Matilde B.Z. Vergara, Isabell Dobrzycki, David J. Wrucke, Carlos S. Zepeda, Jessica J. James, Christopher W. Sundberg, Troy Alan Hornberger

This study identifies myofibril loss as the primary cause of muscle fiber atrophy in aging and disuse, using macroscopic to ultrastructural analyses in humans and mice.

bioRxiv · Feb 18, 2026 · PreprintPhysiology

Mechanical Loading Induces the Longitudinal Growth of Muscle Fibers via an mTORC1-Independent Mechanism

Jamie E. Hibbert, Kent W. Jorgenson, Ramy K. A. Sayed, Hector G. Paez, Marius Meinhold, Corey G. K. Flynn, Anthony N. Lange, Garrison T. Lindley, Philip M. Flejsierowicz, Troy Alan Hornberger

This study shows mechanical loading induces muscle fiber growth through two mechanisms: mTORC1-dependent radial growth and mTORC1-independent longitudinal sarcomere addition.

bioRxiv · Sep 19, 2025 · PreprintPhysiology