Carlos S. Zepeda

This study uses 3D-imaging to assess intrinsic contractile function in aging human skeletal muscle fibers, finding preserved function despite reduced fiber size.

This study identifies myofibril loss as the primary cause of muscle fiber atrophy in aging and disuse, using macroscopic to ultrastructural analyses in humans and mice.

This study shows that myonuclear loss, not senescent myonuclei, is linked to fast fiber atrophy in aging human skeletal muscle.