Author

Isabell Dobrzycki

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:imaging· 2 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Carlos S. ZepedaiD· 3 shared Christopher W. SundbergiD· 3 shared Anthony N. Lange· 1 shared Corey G. K. FlynniD· 1 shared Cory M. DunganiD· 1 shared David J. WruckeiD· 1 shared Hector G. PaeziD· 1 shared Jamie E. HibbertiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

Carlos S. ZepedaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Three-dimensional imaging reveals preserved intrinsic contractile function in aging human skeletal muscle fibers

Carlos S. Zepeda, Laura E. Teigen, Isabell Dobrzycki, Yuan Wen, Christopher W. Sundberg

This study uses 3D-imaging to assess intrinsic contractile function in aging human skeletal muscle fibers, finding preserved function despite reduced fiber size.

bioRxiv · Jun 12, 2026 · PreprintPhysiology

Macroscopic to Ultrastructural Analyses Identify the Loss of Myofibrils as the Primary Mediator of Muscle Fiber Atrophy in Aging and Disuse

Ramy K. A. Sayed, Anthony N. Lange, Hector G. Paez, Jamie E. Hibbert, Marius Meinhold, Corey G. K. Flynn, Matilde B.Z. Vergara, Isabell Dobrzycki, David J. Wrucke, Carlos S. Zepeda, Jessica J. James, Christopher W. Sundberg, Troy Alan Hornberger

This study identifies myofibril loss as the primary cause of muscle fiber atrophy in aging and disuse, using macroscopic to ultrastructural analyses in humans and mice.

bioRxiv · Feb 18, 2026 · PreprintPhysiology

Myonuclear loss, rather than senescent myonuclei, associates with fiber type-specific atrophy in aging human skeletal muscle

Carlos S. Zepeda, Isabell Dobrzycki, Paige Acklie, Cory M. Dungan, Ronald G. Jones, Kevin A. Murach, Christopher W. Sundberg

This study shows that myonuclear loss, not senescent myonuclei, is linked to fast fiber atrophy in aging human skeletal muscle.

bioRxiv · Feb 13, 2026 · PreprintCell Biology