The BAP1 deubiquitinase complex is a general transcriptional co-activator
Antoine Campagne, Dina Zielinski, Audrey Michaud, Stéphanie Le Corre, Florent Dingli, Hong Chen, Ivaylo Vassilev, Ming-Kang Lee, Nicolas Servant, Damarys Loew, Éric Pasmant, Sophie C. Postel-Vinay, Michel Adam Wassef, Raphaël Margueron
The paper identifies BAP1 as a general transcriptional co-activator through CRISPR/Cas9-generated isogenic cell lines and shows it functions independently of the Polycomb machinery.
bioRxiv · Jan 8, 2018 · PreprintGenomics