Author

Ming-Kang Lee

Centre National de la Recherche ScientifiqueORCID 0000-0002-8276-7904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

Alexander MeissneriD· 1 shared Antoine Campagne· 1 shared Audrey Michaud· 1 shared Damarys LoewiD· 1 shared Daniel Minatti Felismino· 1 shared Dina ZielinskiiD· 1 shared Éric PasmantiD· 1 shared Florent DingliiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Alexander MeissnerORCID

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2 papers

Recent·Most cited

Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Minatti Felismino, Jeron Venhuizen, Maria Walther, Alexander Meissner

This study uses temporal PRC2 degradation in embryoid models to reveal lineage-specific gene expression changes and the role of transcription factors in PRC2 loss responses.

bioRxiv · Apr 21, 2026 · PreprintDevelopmental Biology

The BAP1 deubiquitinase complex is a general transcriptional co-activator

Antoine Campagne, Dina Zielinski, Audrey Michaud, Stéphanie Le Corre, Florent Dingli, Hong Chen, Ivaylo Vassilev, Ming-Kang Lee, Nicolas Servant, Damarys Loew, Éric Pasmant, Sophie C. Postel-Vinay, Michel Adam Wassef, Raphaël Margueron

The paper identifies BAP1 as a general transcriptional co-activator through CRISPR/Cas9-generated isogenic cell lines and shows it functions independently of the Polycomb machinery.

bioRxiv · Jan 8, 2018 · PreprintGenomics