Alveolar and airway progenitors converge on an epigenetically encoded profibrotic state
Jessica Liang, Xulun Zhang, Rachel Genova, Anuradha Basyal, Kendall Foster, Qinxue Shen, Christopher Ting, Haichun Pan, Robert P Dickson, Nicole Falkowski, Joshua Franzen, Jason R Spence, Tristan Frum, Cyrina Ostgaard, Cole Weber, , Rachel Lynne Zemans
The paper identifies a conserved profibrotic transitional state arising from alveolar and airway progenitors in fibrosis and shows its epigenetic regulation.
bioRxiv · Nov 10, 2026 · PreprintDevelopmental Biology