Structural and Biophysical Dynamics of Fungal Plasma Membrane Proteins and Implications for Echinocandin Action in Candida glabrata
Jennifer Bo Jiang, Mikhail V. Keniya, Anusha Puri, Xueying Zhan, Jeff Cheng, Huan Wang, Gigi Lin, Yun-Kyung Lee, Nora Jaber, Caifeng Zhao, Cynthia Pang, Yasmine Hassoun, Haiyan Zheng, Erika Shor, Zheng Shi, , Wei Dai
This study investigates the structural and dynamic organization of plasma membrane proteins in Candida glabrata using cryo-ET and live cell imaging, revealing how echinocandin drugs affect their distribution and function.
Nature Communications · Oct 14, 2025Peer-reviewedCell Biology