David S. Perlin

The paper identifies common evolutionary events leading to fungicide persistence in Cryptococcus neoformans clinical isolates and shows ACO2 deficiency as a key predictor of high persistence.

This study investigates the structural and dynamic organization of plasma membrane proteins in Candida glabrata using cryo-ET and live cell imaging, revealing how echinocandin drugs affect their distribution and function.

This study evaluates the infection kinetics and Nirmatrelvir efficacy against Omicron subvariants in transgenic mice, finding that these subvariants show distinct viral dynamics but remain susceptible to the antiviral.

This study identifies a novel FKS1 mutation in Candida lusitaniae that confers echinocandin resistance through activation of the CWI pathway via MKC1.