Caifeng Zhao

Structural and Biophysical Dynamics of Fungal Plasma Membrane Proteins and Implications for Echinocandin Action in Candida glabrata

This study investigates the structural and dynamic organization of plasma membrane proteins in Candida glabrata using cryo-ET and live cell imaging, revealing how echinocandin drugs affect their distribution and function.

Mealtime alters daily rhythm in nuclear O-GlcNAc proteome to regulate hepatic gene expression

This study shows that mealtime affects the daily rhythm of nuclear O-GlcNAc proteome in mice, which regulates hepatic gene expression through interactions with phosphorylation.

Alternative splicing of clock transcript mediates the response of circadian clocks to temperature changes

The paper investigates temperature-sensitive alternative splicing of the clk gene in Drosophila and its role in regulating circadian clock function through phosphorylation site deletion.

KAT2 paralogs prevent dsRNA accumulation and interferon signaling to maintain intestinal stem cells

This study shows that KAT2A and KAT2B prevent dsRNA accumulation and interferon signaling, which is critical for maintaining intestinal stem cells in mice.

CK2 inhibits TIMELESS nuclear export and modulates CLOCK transcriptional activity to regulate circadian rhythms

The paper identifies TIM phosphorylation sites in Drosophila and shows that CK2-dependent phosphorylation of TIM(S1404) regulates nuclear export and circadian rhythms, with implications for human FASPS.