Pantetheinamides that inhibit the growth of intracellular Salmonella Typhimurium
Jacob Pierscianowski, Dustin Duncan, Chunling Blue Lan, Rohit Kholiya, Suzana Diaconescu-Grabari, Farhan Rahman Chowdhury, Ahmed B. Abdelaal, Aracelli Chang, Iain Roe, Shay Heans Moreyra, Sanjay Campbell, Alexandre Pierret, Kamal Adhikari, S GHOSH, Angelos Pistofidis, , Karine Auclair
This study identifies pantetheinamide compounds that inhibit intracellular Salmonella Typhimurium growth by targeting CoA biosynthesis, showing reduced bacterial burden in a murine model.
bioRxiv · Oct 28, 2025 · PreprintMicrobiology