Karine Auclair

This study screens Arctic bacteria to discover antibacterial compounds, identifying koreenceine A from a Pseudomonas isolate and confirming its antibiotic activity through genetic analysis.

This study identifies pantetheinamide compounds that inhibit intracellular Salmonella Typhimurium growth by targeting CoA biosynthesis, showing reduced bacterial burden in a murine model.

This study investigates how Salmonella Typhimurium metabolizes and responds to itaconate, finding that it primarily detoxifies itaconate rather than using it as a carbon source.

This study develops pantothenamide-mimics with thiazole rings to overcome degradation by pantetheinase, showing potent antiplasmodial activity and enzyme selectivity.