Farhan Rahman Chowdhury

This study identifies pantetheinamide compounds that inhibit intracellular Salmonella Typhimurium growth by targeting CoA biosynthesis, showing reduced bacterial burden in a murine model.

This study investigates antibiotic cycling regimens using collateral sensitivity, finding that backward collateral sensitivity can restore antibiotic susceptibility and improve treatment outcomes.

This study identifies a robust collateral sensitivity between tigecycline and polymyxin B in E. coli through laboratory evolution and validates it in clinical isolates.

This study investigates how Salmonella Typhimurium metabolizes and responds to itaconate, finding that it primarily detoxifies itaconate rather than using it as a carbon source.

This study introduces tripartite antibiotic regimens that reverse bacterial resistance by cycling through three drugs, leading to resensitization and reduced fitness costs.

This study evolves high-level resistance to the antibiotic octyl-tridecaptin A1 and polymyxin B in bacteria using a modified SAGE system, identifying mutations in outer membrane proteins as key to resistance.