Mediator subunit MDT-15 promotes expression of propionic acid breakdown genes to prevent embryonic lethality in Caenorhabditis elegans
Grace Ying Shyen Goh, Arshia Beigi, Junran Yan, Kelsie R. S. Doering, Stefan Taubert
The paper shows that MDT-15 is essential for activating propionate shunt pathway genes in C. elegans, preventing embryonic lethality by regulating vitamin B12-dependent gene expression.
G3 Genes Genomes Genetics · Apr 19, 2023Peer-reviewedGenetics