Author

Asami Sakamoto

National Center of Neurology and Psychiatry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Kazumi ShimaokaiD· 3 shared Kei HoriiD· 3 shared Kenji SakimuraiD· 3 shared Kunihiko YamashiroiD· 3 shared Manabu AbeiD· 3 shared Mikio HoshinoiD· 3 shared Saki F. Egusa· 3 shared Satoshi MiyashitaiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Kazumi ShimaokaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

AUTS2, a causative gene for microcephaly, regulates division of intermediate progenitor cells and production of upper-layer neurons

Kazumi Shimaoka, Kei Hori, Satoshi Miyashita, Yukiko Inoue, Nao K N Tabe, Asami Sakamoto, Ikuko Hasegawa, Kayo Nishitani, Kunihiko Yamashiro, Saki F. Egusa, Shoji Tatsumoto, Yasuhiro Go, Manabu Abe, Kenji Sakimura, Takayoshi Inoue, , Mikio Hoshino

This study identifies AUTS2's role in regulating intermediate progenitor cell division and upper-layer neuron production through interaction with PRC2 and repression of genes like Robo1.

The EMBO Journal · Jan 15, 2025Peer-reviewedNeuroscience

AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

Kunihiko Yamashiro, Kei Hori, Suk‐King Lai, Ryo Aoki, Kazumi Shimaoka, Nariko Arimura, Saki F. Egusa, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Takaki Watanabe, Naofumi Uesaka, Masanobu Kano, Mikio Hoshino

This study investigates the role of AUTS2 in cerebellar development, Purkinje cell maturation, and behavioral functions, finding that its loss leads to cerebellar defects and behavioral impairments linked to ASDs.

iScience · Nov 18, 2020Peer-reviewedNeuroscience

AUTS2 regulation of synapses for proper synaptic inputs and social communication.

Kei Hori, Kunihiko Yamashiro, Taku Nagai, Wei Shan, Saki F. Egusa, Kazumi Shimaoka, Hiroshi Kuniishi, Masayuki Sekiguchi, Yasuhiro Go, Shoji Tatsumoto, Mitsuyo Yamada, Reika Shiraishi, Kouta Kanno, Satoshi Miyashita, Asami Sakamoto, , Mikio Hoshino

This study shows that AUTS2 regulates excitatory synapse number to maintain E/I balance, and its loss leads to autistic-like behaviors and increased brain excitability.

iScience · May 18, 2020Peer-reviewedNeuroscience