Yukiko Inoue

The paper introduces two 3D neural networks for segmenting and scoring epithelial cells in cleared mammary tissue, demonstrating their use in quantifying myoepithelial cell proportions during pregnancy-lactation transitions.

Ryanozole, a RyR2-selective stabilizer, prevents stress-induced arrhythmias without impairing cardiac function in CPVT mouse models.

This study identifies spinal oxytocin circuits as a conserved mechanism through which affiliative touch reduces pain and enhances well-being in mice and humans.

This study identifies MEIS1 as a key transcription factor required for the development of Bergmann glia-specific properties in the cerebellum by regulating the expression of BG-specific genes.

The paper identifies vasopressin-to-oxytocin receptor crosstalk in the preoptic area as a key mechanism for paternal caregiving behaviors in male mice.

This study identifies LAMP2B as a mediator of microlipophagy, showing its role in preventing obesity and related metabolic disorders through enhanced lipid hydrolysis.

The paper develops cPcdhβ reporter mouse lines to visualize stochastic expression of cPcdhβ isoforms in vivo and identifies patterns such as cell-type selectivity and developmental regulation.

This study identifies AUTS2's role in regulating intermediate progenitor cell division and upper-layer neuron production through interaction with PRC2 and repression of genes like Robo1.

The paper identifies two molecularly distinct subtypes of sympathetic preganglionic neurons in mice that selectively regulate gastrointestinal and adrenal functions through non-overlapping innervation patterns.

The paper identifies SNUPN variants causing spinocerebellar atrophy by disrupting splicing in Purkinje cells through impaired U1 snRNP nuclear transport.

The paper visualizes homophilic interactions of clustered protocadherin in neurons using a novel FRET probe and finds that these interactions occur at contact sites between neurites and are stable, while synapses show rare homophilic interactions.

The paper identifies a DNAJB4 variant causing chaperonopathy in skeletal muscle, leading to muscle weakness and specific pathological features in type 1 fibers.