ZO-1 shuttles between tight junctions and podosomes by riding ERK activation waves during collective cell migration
Sayuki Hirano, Yohei Kondo, Asayuki Kitajima, Noriyuki Kinoshita, Tetsuhisa Otani, Mikio Furuse, Naoto Ueno, Kazuhiro Aoki
This study shows ZO-1 moves between tight junctions and podosomes during collective cell migration, regulated by ERK activity, and contributes to cell adhesion and movement.
Nature Communications · May 9, 2026Peer-reviewedCell Biology