Mikio Furuse

This study shows ZO-1 moves between tight junctions and podosomes during collective cell migration, regulated by ERK activity, and contributes to cell adhesion and movement.

This study shows that a low-salt diet increases claudin-3 expression in mice, which reduces paracellular sodium permeability, and claudin-3-deficient mice adapt by upregulating other claudins and ENaC to maintain sodium balance.

The paper investigates the role of claudin-11 in forming immunological barriers and supporting spermatogonial proliferation through stem cell factor in mice.

The paper shows that ZO-1/ZO-2-deficient cells are selectively eliminated by cell competition, mediated by supracellular actomyosin cables and Hippo signaling, to maintain epithelial barrier homeostasis.

This study shows low-affinity EGFRLs like EREG and AREG transmit signals more efficiently than high-affinity ligands during collective cell migration and wound healing.

The paper demonstrates mechanical coupling between epithelial cells at apical-apical surfaces during implantation, mediated by extracellular matrix and tight junction molecules.