Sayuki Hirano

This study shows ZO-1 moves between tight junctions and podosomes during collective cell migration, regulated by ERK activity, and contributes to cell adhesion and movement.

The paper reconstitutes planar cell polarity in cultured epithelial cells by integrating Wnt signaling, tissue tension, and Prickle3 overexpression, showing their roles in polarity axis establishment and direction.

This study examines how photothermal therapy affects ERK signaling and intercellular communication in tumor spheroids using FRET sensors and deep learning.