Author

Ashwathi S. Mohan

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Alex Groisman· 1 shared Erik Welf· 1 shared Gaudenz Danuser· 1 shared Kevin M. DeaniD· 1 shared Philippe Roudot· 1 shared Sangyoon J. Han· 1 shared Stacy Y. Kasitinon· 1 shared Tadamoto Isogai· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Alex Groisman

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1 paper

Recent·Most cited

Hyperactive Rac1 drives MAPK-independent proliferation in melanoma by assembly of a mechanosensitive dendritic actin network

Ashwathi S. Mohan, Kevin M. Dean, Stacy Y. Kasitinon, Tadamoto Isogai, Vasanth Siruvallur Murali, Sangyoon J. Han, Philippe Roudot, Alex Groisman, Erik Welf, Gaudenz Danuser

This paper shows that a Rac1 mutation drives melanoma proliferation independently of MAPK signaling by forming a mechanosensitive actin network that inactivates the tumor suppressor NF2/Merlin.

bioRxiv · May 22, 2018 · PreprintCell Biology