Redox imbalance dictates dependence on GOT1 versus GOT2 for rod photoreceptor health during aging and stress
Meini Chen, Eric Weh, Moloy T. Goswami, Katherine M. Weh, Heather M. Hager, Peter Sajjakulnukit, Avi Weingarten, Shubha Subramanya, Nicholas Miller, Sraboni Chaudhury, Emma Piraino, Navdeep S. Chandel, Renee C. Ryals, Costas Andreas Lyssiotis, Thomas J. Wubben
This study shows that GOT1 and GOT2 have opposing roles in rod photoreceptor health, with GOT2 acting as a neuroprotective factor under reductive stress conditions.
Redox Biology · Jun 18, 2026Peer-reviewedNeuroscience