Author

Avinash Y. L. Jadhav

Wake Forest University Health Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:non-human primate· 4 Approach:statistical model· 4 Assay:metabolomics· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Jeannie ChaniD· 4 shared Laura A. CoxiD· 4 shared Michael OlivieriD· 4 shared Ge LiiD· 3 shared Hillary F. HuberiD· 3 shared Kip D. ZimmermaniD· 3 shared Peter W. NathanielsziD· 3 shared Sobha PuppalaiD· 3 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMolecular Biology

Jeannie ChanORCID

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Author profile →

4 papers

Recent·Most cited

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

Luís F. Grilo, Kip D. Zimmerman, Sobha Puppala, Jeannie Chan, Hillary F. Huber, Ge Li, Avinash Y. L. Jadhav, Benlian Wang, Cun Li, Geoffrey D. Clarke, Thomas C. Register, Paulo Jorge Oliveira, Peter W. Nathanielsz, Michael Olivier, Susana P. Pereira, Laura A. Cox

This study identifies age-related metabolic shifts in baboon hearts that promote glycosaminoglycan accumulation via the hexosamine biosynthetic pathway, preceding cardiac hypertrophy.

Advanced Science · Aug 9, 2024Peer-reviewedMolecular Biology

Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders

Laura A. Cox, Sobha Puppala, Jeannie Chan, Kip D. Zimmerman, Zeeshan Hamid, Isaac Ampong, Hillary F. Huber, Ge Li, Avinash Y. L. Jadhav, Benlian Wang, Cun Li, Mark G. Baxter, Carol A. Shively, Geoffrey D. Clarke, Thomas C. Register, , Michael Olivier

The paper integrates multi-omics data from female baboons to identify age-related molecular changes in the prefrontal cortex, revealing altered signaling pathways and potential biomarkers for age-related cognitive decline.

Neurobiology of Aging · Dec 1, 2023Peer-reviewedSystems Biology

Multi-omics Analysis of Aging Liver Reveals Changes in Endoplasmic Stress and Degradation Pathways in Female Nonhuman Primates

Sobha Puppala, Jeannie Chan, Kip D. Zimmerman, Zeeshan Hamid, Isaac Ampong, Hillary F. Huber, Ge Li, Avinash Y. L. Jadhav, Cun Li, Peter W. Nathanielsz, Michael Olivier, Laura A. Cox

This study integrates multi-omics data from female nonhuman primates to identify aging-related molecular changes in the liver, revealing age-associated pathways in endoplasmic stress and degradation.

bioRxiv · Aug 21, 2023 · PreprintMolecular Biology

Integrated Omics Analysis Reveals Sirtuin Signaling is Central to Hepatic Response to a High Fructose Diet

Laura A. Cox, Jeannie Chan, Prahlad Rao, Zeeshan Hamid, Jeremy P. Glenn, Avinash Y. L. Jadhav, Vivek Das, Genesio Mugambi Karere, Ellen E. Quillen, Kylie Kavanagh, Michael Olivier

The paper integrates transcriptomics, proteomics, and metabolomics data from vervet monkeys to identify sirtuin signaling and PPARA network alterations in response to a high fructose diet.

BMC Genomics · Dec 3, 2021Peer-reviewedSystems Biology