Author

Luís F. Grilo

Centro de Neurociências e Biologia CelularORCID 0000-0002-6278-9241Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aaron Warren· 1 shared Adriana Marques-Carvalho· 1 shared Ana Resende-CoelhoiD· 1 shared Ankita Chalke· 1 shared Avinash Y. L. Jadhav· 1 shared Benjamin Stronach· 1 shared Benlian Wang· 1 shared Claudia C.S. ChiniiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aaron Warren

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 11, 2025

Estrogens protect bone mass by inhibiting NAD+ metabolism in osteoclasts

Adriana Marques-Carvalho, Gareeballah Osman Adam, Ankita Chalke…·Maria Almeida

This study shows estrogens protect bone mass by inhibiting NAD+ metabolism in osteoclasts, reducing bone resorption through suppression of SIRT3 activity.

DOI 10.1101/2025.07.11.664289

mousehuman

𝕏 PostBluesky

Molecular BiologyAdvanced SciencePeer-reviewedAug 9, 2024

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

Luís F. Grilo, Kip D. Zimmerman, Sobha Puppala…·Laura A. Cox

This study identifies age-related metabolic shifts in baboon hearts that promote glycosaminoglycan accumulation via the hexosamine biosynthetic pathway, preceding cardiac hypertrophy.

13 citations

non-human primatebulk RNA-seq

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