Michael Olivier

This study identifies age-related metabolic shifts in baboon hearts that promote glycosaminoglycan accumulation via the hexosamine biosynthetic pathway, preceding cardiac hypertrophy.

This study examines the effects of maternal undernutrition on hepatic mitochondrial function in baboon offspring during aging, finding male-specific increases in mitochondrial bioenergetics without changes in plasma metabolites.

The paper identifies diet-responsive eQTLs in baboons exposed to high cholesterol and fat diets, showing their relevance to human metabolic GWAS genes.

The paper integrates multi-omics data from female baboons to identify age-related molecular changes in the prefrontal cortex, revealing altered signaling pathways and potential biomarkers for age-related cognitive decline.

This study integrates multi-omics data from female nonhuman primates to identify aging-related molecular changes in the liver, revealing age-associated pathways in endoplasmic stress and degradation.

This study compares hepatic gene expression in adolescents and adults with NAFLD, finding some similarities but major differences in transcriptomic profiles associated with disease severity.

This study evaluates label-free quantification and missing value imputation methods in non-human primate proteomics to improve data quality and analysis.

The paper integrates transcriptomics, proteomics, and metabolomics data from vervet monkeys to identify sirtuin signaling and PPARA network alterations in response to a high fructose diet.

The paper compares a GC-Orbitrap-MS with FID capabilities to traditional GC-MS for metabolomics of human serum, showing improved quantification and pathway coverage.

A short-term Western diet exposure in baboons caused long-term metabolic changes, suggesting a reset of the metabolic program.