Author

Geoffrey D. Clarke

The University of Texas at San Antonio Health Science CenterORCID 0000-0003-4559-6437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:non-human primate· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hillary F. HuberiD· 3 shared Laura A. CoxiD· 3 shared Michael OlivieriD· 3 shared Peter W. NathanielsziD· 3 shared Avinash Y. L. Jadhav· 2 shared Benlian Wang· 2 shared Ge LiiD· 2 shared Jeannie ChaniD· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Hillary F. HuberORCID

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3 papers

Recent·Most cited

Molecular BiologyAdvanced SciencePeer-reviewedAug 9, 2024

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

Luís F. Grilo, Kip D. Zimmerman, Sobha Puppala…·Laura A. Cox

This study identifies age-related metabolic shifts in baboon hearts that promote glycosaminoglycan accumulation via the hexosamine biosynthetic pathway, preceding cardiac hypertrophy.

13 citations

non-human primatebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivPreprintMay 2, 2024

Perinatal maternal undernutrition in baboons modulates hepatic mitochondrial function but not metabolites in aging offspring.

Daniel Abiodun Adekunbi, Bowen Yang, Hillary F. Huber…·Adam B. Salmon

This study examines the effects of maternal undernutrition on hepatic mitochondrial function in baboon offspring during aging, finding male-specific increases in mitochondrial bioenergetics without changes in plasma metabolites.

DOI 10.1101/2024.05.02.592246

non-human primateproteomics

𝕏 PostBluesky

Systems BiologyNeurobiology of AgingPeer-reviewedDec 1, 2023

Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders

Laura A. Cox, Sobha Puppala, Jeannie Chan…·Michael Olivier

The paper integrates multi-omics data from female baboons to identify age-related molecular changes in the prefrontal cortex, revealing altered signaling pathways and potential biomarkers for age-related cognitive decline.

5 citations

non-human primateproteomics

𝕏 PostBluesky