ImmunologyCellPeer-reviewed
Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency
Shuo Du, Yunlong Cao, Qinyu Zhu…·Junyu Xiao
The paper reports the cryo-EM structure of a potent SARS-CoV-2 NAb, BD-368-2, showing it blocks ACE2 binding and induces structural changes in the spike trimer, distinct from other NAbs.
DOI 10.1016/j.cell.2020.09.035