Author

Hua Xu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Ayijiang Yisimayi· 1 shared Bo Wang· 1 shared Chenggong JiiD· 1 shared Faisal MahmoodiD· 1 shared Guopeng WangiD· 1 shared Hao WuiD· 1 shared Hongyu ZhaoiD· 1 shared James ZouiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Ayijiang Yisimayi

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2 papers

Recent·Most cited

spEMO: Leveraging Multi-Modal Foundation Models for Analyzing Spatial Multi-Omic and Histopathology Data

Tianyu Liu, Tinglin Huang, Tong Ding, Hao Wu, Peter Humphrey, Sudhir Perincheri, Kurt Schalper, Rex Ying, Hua Xu, James Zou, Faisal Mahmood, Hongyu Zhao

spEMO integrates histopathology and spatial multi-omic data using foundation models, improving performance in spatial analysis and medical report generation.

bioRxiv · Jan 13, 2025 · PreprintBioinformatics

Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency

Shuo Du, Yunlong Cao, Qinyu Zhu, Guopeng Wang, Xiaoxia Du, Runsheng He, Hua Xu, Yinghui Zheng, Bo Wang, Yali Bai, Chenggong Ji, Ayijiang Yisimayi, Qisheng Wang, Ning Gao, X. Sunney Xie, , Junyu Xiao

The paper reports the cryo-EM structure of a potent SARS-CoV-2 NAb, BD-368-2, showing it blocks ACE2 binding and induces structural changes in the spike trimer, distinct from other NAbs.

Cell · Nov 1, 2020Peer-reviewedImmunology