Author

B. A. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Leatham· 1 shared B. Z. Stanger· 1 shared E. Stelow· 1 shared J. Gole· 1 shared J. R. Pitarresi· 1 shared K. Cabrera· 1 shared K. E. Lee· 1 shared K. Leong· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. Leatham

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell RNA sequencing reveals microenvironment context-specific routes for epithelial-mesenchymal transition in pancreas cancer cells

B. A. Brown, M. Lazzara

The paper uses scRNA-seq to analyze EMT in pancreas cancer cells under hypoxia or growth factors, identifying context-specific pathways and potential drug targets.

bioRxiv · May 30, 2023 · PreprintCancer Biology

Analytical performance and concordance with next-generation sequencing of a rapid multiplexed dPCR panel for the detection of actionable DNA and RNA biomarkers in non-small cell lung cancer

B. A. Brown, K. Cabrera, J. Gole, B. Leatham, L. Jacky

The paper evaluates a multiplexed dPCR panel for detecting DNA and RNA biomarkers in NSCLC, showing high analytical sensitivity and concordance with NGS.

bioRxiv · May 4, 2023Cancer Biology

A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer

B. A. Brown, P. J. Myers, S. J. Adair, J. R. Pitarresi, S. K. Sah-Teli, L. A. Campbell, W. S. Hart, M. Barbeau, K. Leong, N. Seyler, W. Kane, K. E. Lee, E. Stelow, M. Jones, M. C. Simon, , M. J. Lazzara

This study identifies a hypoxia-driven histone methylation-MAPK feedback loop that sustains EMT in pancreatic cancer, with potential therapeutic implications.

bioRxiv · Oct 19, 2022 · PreprintCancer Biology