Author

J. R. Pitarresi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. K. Rustgi· 1 shared B. A. Brown· 1 shared B. Z. Stanger· 1 shared C. E. Bowman· 1 shared C. F. Lusi· 1 shared C. N. Parikh· 1 shared E. Fernandez Garcia· 1 shared E. Stelow· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. K. Rustgi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nanoparticle delivery of innate immune agonists combines with senescence-inducing agents to mediate T cell control of pancreatic cancer

L. Chibaya, C. F. Lusi, K. D. DeMarco, G. I. Kane, M. L. Brassil, C. N. Parikh, K. C. Murphy, J. Li, T. E. Naylor, J. Cerrutti, J. Peura, J. R. Pitarresi, L. J. Zhu, K. A. Fitzgerald, P. U. Atukorale, M. A. Ruscetti

This paper combines nanoparticle-delivered immune agonists with senescence-inducing agents to enhance T cell responses and control pancreatic cancer in preclinical models.

bioRxiv · Sep 18, 2023 · PreprintCancer Biology

The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation

E. Fernandez Garcia, U. Paudel, M. C. Noji, C. E. Bowman, J. R. Pitarresi, A. K. Rustgi, K. E. Wellen, Z. Arany, J. S. Weissenrieder, J. K. Foskett

This study shows that the mitochondrial Ca2+ channel MCU supports tumor growth by enabling cell cycle progression and proliferation through mitochondrial Ca2+ uptake, despite unchanged mitochondrial function.

bioRxiv · Apr 26, 2023 · PreprintCancer Biology

A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer

B. A. Brown, P. J. Myers, S. J. Adair, J. R. Pitarresi, S. K. Sah-Teli, L. A. Campbell, W. S. Hart, M. Barbeau, K. Leong, N. Seyler, W. Kane, K. E. Lee, E. Stelow, M. Jones, M. C. Simon, , M. J. Lazzara

This study identifies a hypoxia-driven histone methylation-MAPK feedback loop that sustains EMT in pancreatic cancer, with potential therapeutic implications.

bioRxiv · Oct 19, 2022 · PreprintCancer Biology