Author

E. Kilger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Armento· 3 shared M. Ueffing· 3 shared S. J. Clark· 3 shared I. Sonntag· 2 shared A. Jacob· 1 shared A. Murali· 1 shared B. Arango-Gonzalez· 1 shared C. A. Ramlogan-Steel· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

A. Armento

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Author profile →

3 papers

Recent·Most cited

FH loss in RPE cells causes retinal degeneration in a human RPE-porcine retinal explant co-culture model

A. Armento, A. Murali, J. Marzi, B. Arango-Gonzalez, E. Kilger, S. J. Clark, K. Schenke-Layland, C. A. Ramlogan-Steel, J. C. Steel, M. Ueffing

This study shows that loss of FH in RPE cells causes retinal degeneration in a co-culture model with porcine retinal explants, with rod cells being the first to degenerate.

bioRxiv · Jul 26, 2021Cell Biology

CFH loss in human RPE cells leads to inflammation and complement system dysregulation via the NF-B pathway

A. Armento, T. L. Schmidt, I. Sonntag, D. Merle, M.-a. Jarboui, E. Kilger, S. J. Clark, M. Ueffing

This study shows that loss of CFH in RPE cells increases inflammation and disrupts complement regulation via the NF-κB pathway, contributing to AMD pathology.

bioRxiv · Apr 19, 2021Immunology

Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells

A. Armento, S. Honisch, V. Panagiotakopoulou, I. Sonntag, A. Jacob, E. Kilger, M. Deleidi, S. J. Clark, M. Ueffing

This study shows that loss of Complement Factor H in human RPE cells reduces antioxidant capacity and impairs energy metabolism, contributing to AMD pathogenesis.

bioRxiv · Jan 8, 2020Cell Biology