Author

B. Bader-Meunier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Belot· 3 shared A. Lepelley· 2 shared C. Bodemer· 2 shared D. Duffy· 2 shared F. Rieux-Laucat· 2 shared M. Hully· 2 shared M.-L. Fremond· 2 shared Y. J. Crow· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

A. Belot

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation.

C. Cosson, R. Riou, D. Patoli, T. Niu, A. Rey, M. Groslambert, E. Chatre, O. Allatif, T. Henry, F. Venet, F. Milhavet, G. Boursier, A. Belot, Y. Jamilloux, E. Merlin, , B. F. Py

This study functionally characterizes 34 NLRP3 variants associated with CAPS, identifying functional diversity and inhibitor sensitivity, with implications for diagnosis and drug development.

bioRxiv · Sep 22, 2023 · PreprintImmunology

Enhanced inflammatory signaling driven by metabolic switch in Aicardi-Goutieres syndrome

M. Batignes, M. Luka, S. Jagtap, C. de Cevins, I. Nemazanyy, T. Fali, V. Garcia-Paredes, F. Carbone, B. P. Perot, B. Neven, B. Bader-Meunier, P. Quartier dit Maire, M. Hully, A. Belot, A. Lepelley, , M. M. Menager

This study identifies a metabolic switch and loss of HIF-1 activity in AGS patients, showing that stabilizing HIF-1 reduces inflammation and IP-10 production.

bioRxiv · Feb 23, 2023 · PreprintImmunology

Targeting the chemokine receptor CXCR4 with histamine analogue to reduce inflammation in juvenile arthritis: a proof of concept for COVID-19 therapeutic approach

N. Bekaddour, N. Smith, B. Beitz, A. Llibre, T. Dott, A. Baudry, A.-S. Korganow, S. Nisole, R. Mouy, S. Breton, B. Bader-Meunier, D. Duffy, B. Terrier, B. Schneider, P. Quartier, , J.-P. Herbeuval

This study shows that targeting CXCR4 with clobenpropit reduces inflammation in juvenile arthritis and COVID-19 by lowering cytokine levels and immune cell activity.

bioRxiv · Oct 24, 2021 · PreprintImmunology

Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A

A. Lepelley, E. Della Mina, E. Van Nieuwenhove, L. Waumans, S. Fraitag, G. I. Rice, A. Dhir, M.-L. Fremond, M. P. Rodero, L. Seabra, E. Carter, C. Bodemer, D. Buhas, B. Callewaert, P. de Lonlay, , Y. J. Crow

The paper identifies mutations in ATAD3A causing enhanced type I interferon signaling in patients with neurological and autoimmune features.

bioRxiv · Apr 2, 2021Immunology

Heterozygous RELA mutations cause early-onset systemic lupus erythematosus by hijacking the NF-κB pathway towards transcriptional activation of type-I Interferon genes

L. Barnabei, H. Lamrini, M. Castela, N. Jeremiah, M.-C. Stolzenberg, L. Chentout, S. Mirshavalad, A. Bouafia, A. Magerus, M. Moncan, S. Jacques, O. Pelle, V. Bondet, D. Duffy, M. Parisot, , F. Rieux-Laucat

This study identifies heterozygous RELA mutations in early-onset SLE patients, showing they drive type-I interferon gene expression through NF-κB pathway hijacking.

bioRxiv · Apr 27, 2020 · PreprintImmunology