Author

I. Nemazanyy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Research Focus:metabolism & bioenergetics· 3 Assay:metabolomics· 3 Organism:mouse· 3

Frequent Co-Authors

a. charbit· 2 shared A. Jamet· 2 shared D. Euphrasie· 2 shared E. RAMOND· 2 shared F. Tros· 2 shared J. Ziveri· 2 shared M. Coureuil· 2 shared A. Belot· 1 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

a. charbit

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

mTOR Inhibition Suppresses Salinomycin-Induced Ferroptosis in Breast Cancer Stem Cells by Ironing Out Mitochondrial Dysfunctions

E. Cosialls, E. Pacreau, S. Ceccacci, R. Elhage, C. Duruel, C. Desterke, K. Roger, C. Guerrera, R. Ducloux, S. Souquere, G. Pierron, I. Nemazanyy, M. Kelly, E. Dalmas, Y. Chang, , A. Hamai

The paper shows that mTOR inhibition reduces Salinomycin-induced ferroptosis in breast cancer stem cells by modulating iron flux and mitochondrial function.

bioRxiv · May 2, 2023Cancer Biology

Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis

C. Patitucci, J. D. Hernandez Camacho, E. Vimont, T. Cokelaer, T. Chaze, Q. Giai Giainetto, M. Matondo, A. Gazi, I. Nemazanyy, D. A. Stroud, D. H. Hock, E. Donnarumma, T. Wai

This study shows that deleting Mtfp1 in hepatocytes increases mitochondrial respiration and protects against fatty liver disease.

bioRxiv · Apr 26, 2023 · PreprintPhysiology

ATP citrate lyase is an essential player of the metabolic rewiring induced by PTEN loss during T-ALL development.

G. Andrieu, G. Hypolite, E. Balducci, C. Costa, E. Verhoeyen, I. Nemazanyy, G. Panasyuk, K. Wellen, E. Macintyre, V. Asnafi, M. Tesio

This study identifies ATP citrate lyase (ACLY) as a critical metabolic driver in PTEN-deficient T-ALL, showing its essential role in disease progression and therapeutic targeting potential.

bioRxiv · Mar 27, 2023Cancer Biology

Enhanced inflammatory signaling driven by metabolic switch in Aicardi-Goutieres syndrome

M. Batignes, M. Luka, S. Jagtap, C. de Cevins, I. Nemazanyy, T. Fali, V. Garcia-Paredes, F. Carbone, B. P. Perot, B. Neven, B. Bader-Meunier, P. Quartier dit Maire, M. Hully, A. Belot, A. Lepelley, , M. M. Menager

This study identifies a metabolic switch and loss of HIF-1 activity in AGS patients, showing that stabilizing HIF-1 reduces inflammation and IP-10 production.

bioRxiv · Feb 23, 2023 · PreprintImmunology

The Pentose Phosphate Pathway constitutes a major metabolic hub in pathogenic Francisella

H. Rytter, A. Jamet, J. Ziveri, E. RAMOND, M. Coureuil, P. Lagouge-Roussey, D. Euphrasie, F. Tros, N. Goudin, C. Chhuon, I. Nemazanyy, F. E. de Moraes, C. Abate, I. C. Guerrera, a. charbit

This study investigates the role of the pentose phosphate pathway in Francisella novicida's intracellular survival and metabolism, showing its critical connections to other metabolic pathways.

bioRxiv · Jan 15, 2021Microbiology

Transketolase of Staphylococcus aureus is involved in the control of master regulators of stress response during infection

X. Tan, E. Ramond, a. jamet, B. Decaux-Tramoni, M. Dupuis, d. euphrasie, F. Tros, I. Nemazanyy, J. Ziveri, X. Nassif, A. Charbit, M. Coureuil

This study shows that transketolase in S. aureus affects stress response regulators, impacting bacterial proliferation during infection.

bioRxiv · Feb 15, 2019Microbiology