Author

B. Caffrey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:clustering· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

S. Subramaniam· 2 shared A. Berezuk· 1 shared A. V. Maltsev· 1 shared K. Tuttle· 1 shared L. Ferrucci· 1 shared L. M. Hartnell· 1 shared M. Gonzalez-Freire· 1 shared S. Chittori· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

S. Subramaniam

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Author profile →

2 papers

Recent·Most cited

Cryo-EM reveals disrupted human p97 allosteric activation by disease mutations and inhibitor binding

B. Caffrey, X. Zhu, A. Berezuk, K. Tuttle, S. Chittori, S. Subramaniam

This study uses cryo-EM to analyze disease mutations and inhibitor binding in p97, revealing how these affect allosteric activation and provide insights into their mechanistic link to dysfunction.

bioRxiv · Aug 10, 2021Biochemistry

Automated methods for 3D Segmentation of Focused Ion Beam-Scanning Electron Microscopic Images

B. Caffrey, A. V. Maltsev, M. Gonzalez-Freire, L. M. Hartnell, L. Ferrucci, S. Subramaniam

The paper introduces automated methods for 3D segmentation of FIB-SEM images, significantly improving analysis speed compared to manual approaches.

bioRxiv · Jan 1, 2019Cell Biology