Author

B. Chia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

J. Hu· 1 shared J. Yap· 1 shared J. Yuan· 1 shared M. Wang· 1 shared W. H. Ng· 1 shared X. Huang· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

J. Hu

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1 paper

Recent·Most cited

AMPKi overcomes the paradoxical activation of CRAF driven by RAF inhibitors through blocking the 14-3-3 binding to its carboxyl-terminus

J. Yuan, W. H. Ng, J. Yap, B. Chia, X. Huang, M. Wang, J. Hu

This study identifies AMPKi as a compound that blocks 14-3-3 binding to CRAF, overcoming RAF inhibitor resistance by preventing paradoxical CRAF activation in cancer cells.

bioRxiv · Jan 30, 2018Cancer Biology