Author

W. H. Ng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

J. Hu· 2 shared J. Yap· 2 shared J. Yuan· 2 shared M. Wang· 2 shared A. S. G. Lee· 1 shared B. Chia· 1 shared C. R. Myers· 1 shared H. Xia· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

J. Hu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A time for every purpose: using time-dependent sensitivity analysis to help understand and manage dynamic ecological systems

W. H. Ng, C. R. Myers, S. McArt, S. Ellner

This paper introduces time-dependent sensitivity analysis (TDSA) to assess how time-specific changes in ecological models affect outcomes, using case studies to demonstrate its insights and limitations.

bioRxiv · Apr 13, 2023Ecology

Engineering 3D Vascularized Adipose Tissue Construct using a Decellularized Lung Matrix

M. K. DeBari, W. H. Ng, M. D. Griffin, L. E. Kokai, K. G. Marra, J. P. Rubin, X. Ren, R. D. Abbott

This study engineers vascularized adipose tissue grafts using a decellularized lung matrix, showing successful integration of adipose cells and endothelial cells in perfusion cultures.

bioRxiv · Jun 22, 2021Bioengineering

The Dimer-dependent Catalytic Activity of RAF Family Kinases Is Revealed Through Characterizing Their Oncogenic Mutants

J. Yuan, W. H. Ng, P. Y. P. Lam, Y. Wang, H. Xia, J. Yap, S. P. Guan, A. S. G. Lee, M. Wang, M. Baccarini, J. Hu

This study identifies dimer-dependent catalytic activity in RAF family kinases through analysis of oncogenic mutants, revealing differential inhibitor resistance and MEK phosphorylation mechanisms.

bioRxiv · Jun 4, 2018Cancer Biology

AMPKi overcomes the paradoxical activation of CRAF driven by RAF inhibitors through blocking the 14-3-3 binding to its carboxyl-terminus

J. Yuan, W. H. Ng, J. Yap, B. Chia, X. Huang, M. Wang, J. Hu

This study identifies AMPKi as a compound that blocks 14-3-3 binding to CRAF, overcoming RAF inhibitor resistance by preventing paradoxical CRAF activation in cancer cells.

bioRxiv · Jan 30, 2018Cancer Biology